TRACKING LEUKOCYTES FROM IN VZVO VIDEO MICROSCOPY USING l\rlORPHOLOGICAL ANISOTROPIC DIFFUSION

نویسندگان

  • Scott T. Acton
  • Klaus Ley
چکیده

The study of inflammatory disease hinges upon the behavior and movement of leukocytes and their interaction with the endothelium. We put forth a method for tracking leukocytes in vivo, whereas tracking has been demonstrated previously only for in vitro experiments. The tracker is based on the enhancing capability of morphological anisotropic diffusion, a partial differential equation model for adaptively filtering imagery that retains structures of interest. Morphological anisotropic diffusion excels over standard diffusion in Ihe ability to preserve objects of a certain shape and scale, and it improves upon standard morphological filters in terms of edge preservation and adaptive smoothing. We use the video frames enhanced by morphological diffusion for edge-based registration and background removal in the tracking process.

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تاریخ انتشار 2004